November 1, 2017 Bill Still

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Anti-Aging Stem Cell Treatment

Synopsis: Well, stem cell therapy is getting ready to move into the mainstream. Senior tennis players have already heard that existing stem cell therapy is working near-miracles at regenerating shoulders and knees at a cost of about $5,000 a pop. But Phase 1 and Phase 2 trials have now reported findings for the effects of a particular type of stem cell, known as MSCs, that tend to reverse frailty in a small group of patients with an average age of 76. Phase 1 & 2 trials are designed to just test the safety of proposed treatments, however, doctors have been amazed at lasting improvements 6 months after the trials ended in overall fitness, tumor necrosis factor levels and overall quality of life. According to Dr. David G. Le Couter and colleagues, writing in a guest editorial in “The Journals of Gerontology: "There are always caveats associated with interpreting efficacy in small numbers of subjects, yet it is remarkable that a single treatment seems to have generated improvement in key features of frailty that are sustained for many months," Dr. Joshua M. Hare, Director of the Interdisciplinary Stem Cell Institute at the University of Miami School of Medicine commented: "With the aging of the population, stem cells hold great promise to treat aging-related disability and frailty, improving physical capacity and quality of life. "There is no FDA approved treatment for aging frailty and an enormous unmet need that will only increase with the changing demographics." The next step is a phase 2b clinical trial is being mounted which will involve 120 subjects in 10 locations. After that, a large randomized Phase 3 clinical trial should pave the way for final public approval of the new treatment.